Home to legendary writer Ernest Hemingway for the last ten years of his life, this location is where he penned some of his most famous novels, including For Whom the Bell Tolls and Farewell to Arms. Tour guides will inform you about the infamous writer's works, and memorabilia will grant you a glimpse into his life. After your tour, stroll through the adjacent garden.

An excellent location if you're looking for a respite from other tourists, the Key West Butterfly and Nature Conservatory contains some 60 species of butterfly that flutter through a large glass-domed aviary. There are also 20 species of exotic birds in the conservatory, as well as over 3500 species of plants. A serene, fragrant oasis, this spot is perfect for nature enthusiasts.

History buffs, look no further than the Harry S. Truman Little White House. Originally constructed in 1890 as a naval station during the Spanish-American War, it was, in 1946, converted into the president's winter white house. Since then, many presidents have come here to unwind. Today, it is a museum that showcases Key West's history. Afterwards, enjoy a stroll through the home's botanical gardens.